POLYETHYLENE GLYCOL (PEG 400 PH)
POLYETHYLENE GLYCOL (PEG 400 PH) is a chemical product and Arena Petro Gas is in position to supply and export it directly from the top producers through its trading services according to the following specification and technical properties.
POLYETHYLENE GLYCOL (PEG 400 PH) is a low-molecular-weight grade of polyethylene glycol, a polyether compound derived from petroleum. It is a clear, colorless, viscous liquid with a molecular weight of 380-420 g/mol and a density of 1.128 g/cm^3^. It has a strong hydrophilic property, meaning that it can dissolve in water and other polar solvents, but not in aliphatic hydrocarbons and diethyl ether.
One of the main uses of PEG 400 PH is as an excipient in pharmaceutical formulations, such as oral, topical, and parenteral dosage forms. It can act as a plasticizer, surfactant, suppository base, ointment, solvent, and capsule and tablet lubricant. It can also enhance the solubility and bioavailability of poorly water-soluble drugs by forming complexes with them. Due to its low toxicity, PEG 400 PH is widely used in various medicines, such as laxatives, bowel irrigation solutions, constipation treatments, and gene therapy vectors.
Another use of PEG 400 PH is as a PEGylation agent for protein drugs and drug carriers. PEGylation is the process of attaching PEG chains to biomolecules to improve their stability, circulation time, immunogenicity, and efficacy. PEG 400 PH can be covalently or non-covalently linked to proteins, peptides, antibodies, liposomes, nanoparticles, and other drug delivery systems. PEGylation can also modify the pharmacokinetics and pharmacodynamics of drugs by altering their distribution, metabolism, and elimination.
PEG 400 PH is used in various industries, such as:
- personal care products
- food additives
- detergents, lubricants
It can provide moisturizing, emulsifying, thickening, softening, antistatic, and anti-corrosion effects. It can also act as a humectant, dispersant, carrier, binder, filler, and stabilizer.
The technical specifications of PEG 400 PH :
- Appearance: clear liquid - Color (APHA): max 10 - pH: 5-7 - Specific gravity (25°C): 1.125-1.135 - Viscosity (25°C): 85-95 cSt - Hydroxyl value: 264-300 mg KOH/g - Water content: max 0.5% - Molecular weight: 380-420 g/mol